THE DISTINCT CLINICAL TRAJECTORY, METASTATIC SITES, AND IMMUNOBIOLOGY OF MICROSATELLITE-INSTABILITY-HIGH CANCERS

The distinct clinical trajectory, metastatic sites, and immunobiology of microsatellite-instability-high cancers

Microsatellite-instability-high (MSI-H) cancers form a spectrum of solid organ tumors collectively known as Lynch Syndrome cancers, occurring not only in a subset of colorectal, endometrial, small bowel, gastric, pancreatic, and biliary tract cancers but also in prostate, Axes breast, bladder, and thyroid cancers.Patients with Lynch Syndrome harbor

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Drivers of and barriers to the adoption of green fleet management practices in Zimbabwe: A case study of the funeral assurance sector

Background: For complex fleet operations (e.g.unpredictable routing multiple corpse destinations, longer driver working hours and rough terrains) witnessed in the funeral assurance companies, it is increasingly difficult to strike a balance between cost-effectiveness and reducing environmental impacts.Existing studies do not address this Vacuum Spe

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Neurons in the barrel cortex turn into processing whisker and odor signals: a cellular mechanism for the storage and retrieval of associative signals

Associative learning and memory are essential to logical thinking and cognition.How the neurons are recruited as associative memory Lacrosse - Accessories - Miscellaneous cells to encode multiple input signals for their associated storage and distinguishable retrieval remains unclear.We studied this issue in the barrel cortex by in vivo two-photon

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